I have seen the Speciale No.5 formulation change over the years. At one time this highly effective blemish treatment was a bi-phase formulation that required dipping a cotton swabs deep into the center of the bottle so not to disturb the active ingredients. Now this all-in-one formulation is effortless to use and the precision applicator is a plus. It is rare to find active, blemish-reducing ingredients such as precipitated sulphur in modern skincare formulations, but thankfully Speciale No.5 continues to feature it -- nothing reduces the redness and irritation of a pimple or blemish as effectively as precipitated sulphur. Speciale No.5 is particularly effective when applied at night, to alternate with Pâte Grise l'Originale. With those 2 Payot products, blemishes don't stand a chance. A must-have for blemish-prone skin.